What is Bharat Biotech’s intra-nasal Covid-19 vaccine Incovacc | India News


NEW DELHI: Intranasal Covid vaccine from Bharat Biotech Incovacc It has received government approval for use as a booster dose in the mass inoculation program across the country. It can be given to people over the age of 18, and will first be made available in private hospitals.
Here’s everything you need to know about the nasal vaccines developed by Bharat Biotech and Incovacc:
Advantages of intranasal vaccines:

  • The nasal passage has excellent vaccine uptake potential due to the organized immune system of the nasal mucosa.
  • The delivery process is non-invasive and needle-free.
  • This eliminates the risks associated with needles such as injury and infection.
  • Due to its simple delivery mechanism, it does not require trained healthcare personnel.

What is Incovacc by Bharat Biotech?
Bharat Biotech claims it is a new intranasal adenovirus-vectored vaccine for COVID-19. It stimulates a broad immune response: neutralizing mucosal IgG, IgA and T-cell responses, he says. It also induces an immune response at the site of infection (in the nasal mucosa), which is essential to block the infection and transmission of COVID-19.
It will be given through the nose, as a series of 2 doses, for 4 weeks. A total of 8 drops (0.5 ml per dose), 4 drops are given in each nostril.
The company has detailed the results achieved in several Incovacc trials:

  • In a phase 3 clinical trial conducted in 3000 participants, Incovacc has been shown to produce good immunity after 2 doses for 4 weeks.
  • Headache, fever, runny nose, sneezing were reported as possible side effects, and a severe allergic reaction was said to be “rare”.
  • The company recommends not receiving a dose if: i) Have had a severe allergic reaction to any component of the vaccine ii) Have had a severe allergic reaction after a previous dose of this vaccine iii) Are currently suffering from an acute infection or fever.

The company clearly states that “there is no possibility of vaccination with Incovacc after the COVID-19 immunization.

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